BY V.J Wakefield
It may seem hard to believe this, but it is absolutely true. There is a new drug, called 3K3A-APC, which may prevent Alzheimer’s disease. According to the website Medical News Today called Experimental drug may prevent Alzheimer’s disease written by Tim Newman and fact-checked by Isabel Godfrey, it was written that there is “A drug that scientists are currently developing to treat stroke survivors might also help stave off Alzheimer’s disease” (Newman para 1). This suggests scientists are developing a new kind of drug which, according to the article, is called “3K3A-APC” (Newman para 10).
So what is it? Well according to the article, ” 3K3A-APC is a modified version of activated C protein, which is a blood-based protein that protects brain cells and blood vessels from damage due to inflammation” (Newman, para 10). As stated above, the activated C protein is an influential portion of the new drug. What it really is, is ” a powerful anticoagulant. However, the alterations that scientists have made to the newly modified version has reduced its anticoagulant properties by around 90 percent while maintaining its protective benefits” (Newman para 11). The article also lays out how the new drug actually works, however you have to understand what it is fighting against, which is BACE1. This is an enzyme which is involved in the creation of the plaques that is in beta-amyloid, the enzymes that create Alzheimer’s disease. This is what they are trying to get rid of.
So, now onto what the drug actually does. This medication does not act like a regular Alzheimer’s drug. According to the article, ” In the past, scientists have tried using various compounds to block BACE1. So far, this has not led to new drugs. However, they have shown that interfering with BACE1 reduces Alzheimer’s plaques in the brain. This current medication uses a slightly different approach as it blocks the production of the enzyme rather than blocking the enzyme itself” (Newman para,22).
However, it has to be apparent that this is just in the beginning stages of development and that it has some side effects involved. As stated, “The drug is currently under development to treat brain bleeds in people who have experienced a stroke. So far, the drug seems to reduce bleeding in the brain with few side effects or safety concerns” (Newman para 13). Additionally, they have said that the testing had “… encouraging results” (Newman para 12).
Please read the article that I have used for this piece:
Here is the citation for credit reasons:
Newman, Tim. “Experimental Drug May Prevent Alzheimer’s Disease.” Medical News Today, MediLexicon International, 16 Jan. 2019, http://www.medicalnewstoday.com/articles/324172.php.
Please comment what you think about this new finding and praises to God!
Thank you for reading!